群馬大学大学院医学系研究科 医科学専攻(博士課程) 平成30年度入学案内(英語版)

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RegionMajor FieldContact InformationMain contents of research and key wordsBasic MedicineParasitologyHajime HisaedaExt. 8024 hisa@gunma-u.ac.jpMalaria is one of the most life-threatening infections like AIDS and tuberculosis. Our research interest is host-parasite relationship in malaria. Specifically, immune responses to malaria parasites and pathogenesis of malaria parasites are analyzed in detail. We aim to develop vaccines and drugs to control malaria by revealing host-parasite relationship from both host and parasite points of view.【Keywords】Malaria, host-parasite relationship, immunity, vaccinePublic HealthHiroshi KoyamaExt. 8010hkoyama@gunma-u.ac.jpPublic Health is the art and science to delineate the environmental and social　determinants of health, and to reduce the harmful factors and to promote the supportive factors for health through the organized community e orts. Our research topics include, the protective e ect of trace elements on the development of cancer and metabolic syndrome, analytical studies of trace elements using HPLC-ICP-MS method, depression screening-test for the suicide prevention, and the epidemiology of the relationship between QOL and insurance system and community organization. We also examine health equity and public health ethics.【Keywords】trace element, selenium, cancer prevention, depression screening, and epidemiology, public health ethicsLegal MedicineYoshihiko KominatoExt. 8030 kominato@gunma-u.ac.jpLegal medicine is essentially the application of scienti c methods and techniques to matters involving the public: that covers a lot of ground. Every science from chemistry to medicine, from biology to statistics, from dentistry to anthropology, can be a forensic science if it has some applications to the law or public matter. Especially, our group has been focusing on personal identification, which is one of the important matters of legal medicine in Japan. We have performed researches on ABO blood group, which is one of the important genetic markers in human identification. Based on experimental procedures and human genetic analysis of weak phenotypes, we have investigated transcriptional regulation of the ABO gene.【Keywords】Legal medicine, personal identi cation, ABO blood group, transcriptionMedical Philosophy and EthicsKenji HattoriExt. 8037 hattorik@gunma-u.ac.jpMedical practices in the clinical setting as one of existential situations are fraught with troublesome problems in terms of actual human ways of life. Clinical ethics is tackling them by, not applying some general principles or abstract doctrines mechanically to every case, but paying close attention to the individual circumstances of each case. We have been involved in the groundwork for the methodology of clinical ethics from the perspective of hermeneutics and philosophy of literature. Ethical problems in preventive medicine, the method of teaching medical ethics, meta-ethical approaches to medical ethics, and critically examining the fundamental concepts such as health and disease, are also of our core concern.【Keywords】clinical ethics, medical ethics, philosophy of medicine, medical ethics educationClinical MedicineCardiovascular MedicineMasahiko KurabayashiExt. 8140mkuraba@gunma-u.ac.jpThis department aims to elucidate the molecular mechanisms for a variety of cardiovascular disease, including atherosclerosis, arrhythmia, and heart failure.In particular, we have been interested in the identi cation of biomarkers that have incremental value for prevention of cardiovascular disease, and key molecules that are targetable by drugs. Furthermore, with the advent of human genome science as well as cell biology, we seek for the development of novel therapeutic strategies for atherosclerosis, fatal arrhythmia, and heart failure.【Keywords】 vascular biology, atherosclerosis, heart failure, arrhythmia, myocardial infarction, transcription factors－129－