群馬大学大学院医学系研究科 医科学専攻(博士課程) 平成30年度入学案内(英語版)

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RegionMajor FieldContact InformationMain contents of research and key wordsClinical MedicineClinical LaboratoryMedicine Masami MurakamiExt. 8550mmurakam@gunma-u.ac.jpThe following studies are conducted in our department. 1) Studies on the genetic analysis and preventive medicine: The development and clinical application of new methods for clinical laboratory testing including genetic analysis.2) Studies on the lifestyle-related diseases and atherosclerosis: The clinical and basic studies of lifestyle-related diseases including obesity, diabetes mellitus and dyslipidemia that result in atherosclerosis, especially focusing on energy expenditure, glucose metabolism, lipid metabolism, and insulin and thyroid hormone actions. 3) Studies on the sports medicine: The application of novel biomarkers to support training of athletes.4) Studies on the infection control: The study of infection control in the hospital, including the detection of drug resistant bacteria and the prevention of viral infection.【Keyword】genetic analysis, preventive medicine, lifestyle-related diseases, atherosclerosis, sports medicine, infection controlHuman PathologyHideaki YokooExt. 7970 hyokoo@gunma-u.ac.jpPathology has dual aspects, one is basic science, and the other is clinical medicine practicing diagnostic works. Currently, the Department of Human Pathology is positioned in the clinical group. We routinely carry out pathological diagnosis (biopsy, cytology, autopsy), and also explore pathologic basis of diseases as well as novel therapy. Especially, our research group consistently plays a central role of brain tumor pathology of Japan for decades.【Keywords】human pathology, neuropathology, molecular pathology, diagnostic pathology, brain tumor, translational researchDiagnostic PathologyTetsunari OyamaExt. 7980 oyama@gunma-u.ac.jpOur department has focused on “cancer”, especially on tumor pathology and diagnostic pathology. Various organs, for example, breast, uterine cervix, oral and head and neck, bone and soft tissue, prostate and digestive organs are our subjects of research. Clinicopathological approach with surgical specimens is our main method about carcinogenesis, cancer progression and cancer therapy. Recent projects in our department are as to mutation of oncogene and suppressor gene and expression of cancer related proteins. We have been studying on HPV infection and carcinogenesis. 【Keywords】cancer, tumor pathology, oncogene, tumor progression, protein expression, breastPediatricsHirokazu ArakawaExt. 8200 harakawa@gunma-u.ac.jpVarious diseases in children are closely related to the growth and development of individuals. In addition, the diseases may be caused by breakdown of defense mechanism and homeostasis in response to ambient stimuli. Our aim is to reveal the mechanisms of mucosal immunity related to several infections, the role of autophagy needed to maintenance of intracellular homeostasis, and new genetic mutation and epigenetics related to development of diseases.【Keywords】Allergic diseases, neurodegenerative disorder, acute leukemia, nephrosis, in ammatory bowel diseases.Obstetrics and GynecologyHiroshi Kishi（Associate Professor）Ext. 8423hrskishi@gunma-u.ac.jpThe understanding of hormonal effects and interactions on the hypothalamo-pituitary-ovarian axis is important for comprehending reproductive physiology and pathophysiology. The hormones work on the axis in a well-coordinated way and maintain physiological homeostasis. The aim of our research is to understand the functions of hormones at the molecular level, leading to the discovery of biologically active substances such as hormones and growth factors and their functional mechanisms. Our research involves the interrelationship between structures and functions of hormone receptors to elucidate the functions and mechanisms of actions of gonadotropin receptors【Keywords】LH receptor, FSH receptor, mutation, intracellular signal transduction, Vitamin A－134－