15AgrobioscienceThis laboratory is devoted to research and education for chemi-cal synthesis of biologically active natural organic compounds and the identification of structure–activity relationships, lever-aging organic synthetic approaches.Natural Products ChemistryParasitic plant Strega hermonthica at Sudan (center). Germination stimulant:stigolactone (Upper left). Nuclear Magnetic Resonance spec-trometer(Upper right).Glowing bivalve mollusk Pholas dactylus (Upper left). its blue biolu-minescence(Upper right).Organic substance for the biolumi-nescence; dehydrocoelenterazine(Center). Provides students with research and education programs that clarify the living organisms ingest and produce, the chemical structure and action in the environment around the organisms, and diverse life systems at the molecular level, and that leverage, synthesize, control and develop them.Applied Chemistry in BioscienceStudents actively engaged in experi-mentation with laboratory animals and cell culturesDiscovery of the functions of food elements will contribute to disease preventionFood and Nutritional ChemistryNutritional and non-nutritional components of food mediate, either directly or indirectly, the physiological functions of the human body via the signal transduction pathways. This laborato-ry focuses on the elucidation of regulatory mechanisms at the molecular and organismal levels. It also provides research and education concerning the development of functional foods. Anti-allergic potentialAnti-tumor potentialDetoxificationImmune modulationlifestyle-related, immunologic, and other disordersEsthetic potentialDiseasesOur laboratory investigates the biological and biochemical activ-ities of animals (eel, silkworm), plants (Arabidopsis, herbs), and microbes (E. coli, koji) on the basis of gene expression protein structure and function, and their molecular regulatory systems. Furthermore, our research and education are aimed to contrib-ute the application of the biological enzymes and chemicals in the agricultural, food, and fine chemical industries.Biological ChemistryRight: Crystal sturucture of GTP binding proteinMiddle: Arabidopsis seedlings of wild type (upper left) and plastidic RNA poly-merase-deficient mutants.Left: An enzyme-substrate binding analysis by the molecular dynamics simula-tion.Physical Chemistry for Environmental MoleculesOur laboratory focuses on organisms that utilize light energy for their life activities and systematically analyzes their functional proteins through biophysical and biochemical approaches. This enables us to elucidate the essence of important biochemical phe-nomena at the molecular level, while also conducting educational and research activities to effectively utilize these findings.Purple photosynthetic bacteria inhabiting extreme environments : Thermophile, Halophile, Psychrophile, Acidophile (left). Mechanism of near-infrared (NIR) light resource utilization by purple photosynthetic bacteria (right). Purple photosyn-thetic bacteria can perform photosynthesis using low-energy NIR light that is unused by plants and other phototrophs. The heart of the purple bacterial photo-synthesis is the light-harvesting complex 1-reaction center (LH1-RC) pigment-pro-tein complex. We aim to utilize NIR light energy as a available resource by employ-ing biochemical, physicochemical, and structural biological approaches to inves-tigate the structure-function relationship of the LH1–RC complexes.
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