16DGKβ KO mouse, which shows impairment of memory and its neurons has less branches, indicat-ing importance of DGKβ in morpho-logical change of neurons and higher brain function.Immunofluorescent staining and tissue special staining of cultured animal cellsOur research laboratory is focusing on the proteins and lipids which are major ingredients of animal resources.Specifically, we investigate function of enzymes and lipids to find new markers for quality control of food and some diseases, and to develop functional foods, health care products, and med-icine. In the research, we utilize knockout mice and cultured animal cells focusing on signal transduction and microbiota.On the other hand, proteins and lipids are important factors in the flavor and texture of foods. We also investigate bioactive compounds in those constituents and their digestion mecha-nism and conduct research aimed at increasing the value of food and livestock products.Chemistry and Utilization of Animal Production Resources(Clockwise from upper left) Halotolerant hydrolytic enzymes producing Bacil-lus sp., Aspergillus repens and A. glaucus for Katsuo bonito fermentation, eggshell membrane degrading Pseusomonas sp., thermotolerant Streptomyces spp. isolated from Thai land, photosynthetic Cyanobacterium, thermophilic purple sulfur photosynthetic bacteriumFor the purpose of utilizing microbial resources, this laboratory isolated useful natural microorganisms and characterizes their enzymatic and genetic traits. The research and educational activities of this laboratory are aimed at applying microbial enzymes to selective useful compounds and extraction of bio-logically active substances from biomass residues. This laborato-ry also focuses on essential understandings of reaction mecha-nisms and structures of biologically functional proteins by utiliz-ing methodologies of biophysical chemistry.Environmental MicrobiologyEstimation methods for functions of food components.Prevention effects of food compo-nents on hyperglycemia.The research and education interests of this laboratory relate to overcoming challenges concerning human health, food supply, and environmental conservation. For this purpose, researchers work to identify useful biological capabilities and functional biomolecules, and to clarify their mechanisms of action.Biochemistry FrontiersPhytochemistryThis laboratory implements research and education aimed at pro-moting basic understanding and practical applications of plant functions. The interests of this laboratory include analysis and elucidation of the following topics: chemical structure, biosynthe-sis, and mechanisms of action of secondary metabolites of plant origin; interactions between plants and living organisms in their periphery; and plant responses to environmental stimuli.Elucidation of chemical structure of hatching factor for potato cyst nema-tode and its biosynthesisVisualization of volatile-mediated chemical communication between plants by fluorescence microscopy
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